Position
Senior Lecturer (Neurophysiology)
Qualifications
BSc(Hons) PhD DipEd (NE)
Dr Burne lectures in the faculty's undergraduate and postgraduate neuroscience programs. His lectures cover introductory and applied neurophysiology but focus on the control of movement and posture with an emphasis on movement disorders including stroke, spinal cord injury and Parkinson's disease.
Research field
Reflexes and limb biomechanics in health and disease
Muscle reflexes make important adjustments to the biomechanics of the limb in different tasks. This adaptive role is frequently impaired in movement disorders and contributes to observed abnormal postures and movements such as those seen in stroke and Parkinson's disease. Parallel measures of limb biomechanics (joint stiffness, force and velocity relationships) and reflex activity (extracted from surface EMG) are providing a new perspective on these problems.
Serajul & Aparna are collecting reflex EMG data in response to mixed nerve stimulation.
1. The contribution of stretch reflexes to joint stiffness in posture and voluntary movement
A servo-controlled DC torque motor is being used to deliver stretch perturbations to muscles of the upper and lower limbs at rest and during voluntary contractions. The tonic stretch reflex and mechanical responses to the perturbation are extracted at different phases of postural and movement tasks.
Publications
Leao RN, Burne JA. Continuous wavelet transform in the evaluation of stretch reflex responses from surface EMG. J Neurosci Methods. 133(1-2):115-25, 200.
Leao RN, Burne JA. Identification of reflexive and non-reflexive components of limb stiffness. World congress on Neuroinformatics. F. Rattay Ed. Part 1, pp38. Vienna. 2001.
Leao RN, Burne J. Identification of reflexive and non-reflexive components of limb stiffness. In: Pilowsky P (ed) Proc Aust Neurosci Soc. 2002.13:123.
Leao RN, Burne J. Muscle history and the tonic stretch reflex. IUPS Satellite"Movement and Sensation", Cairns, 2001.
Leao RN, Burne J. The influence of joint angle on tonic stretch reflex tuning. IUPS satellite"Movement and Sensation", Cairns, 2001.
2. Normal and pathological forms of muscle tremor
Muscle tremor is a factor limiting performance in tasks of the upper limb. Tremor in the context of neurological disease may increase in amplitude to the extent that severe disability results. This research has focussed on mechanisms underlying normal and pathological tremor and the application of quantitative measurement to clinical evaluation and therapy.
Publications
Burne JA, Blanche T, Morris J. Muscle loading as a method to isolate the underlying components of parkinsonian and essential tremor. Muscle and Nerve, 2004, 30:347-355.
Burne J, Blanche T, Morris J. Electrical stimulation of muscle tendons in essential tremor. Muscle and Nerve 2002, 25:58-64
Burne J, Hayes M et al. The contribution of tremor studies to diagnosis of Parkinsonian and Essential tremor: a statistical evaluation. Journal of Clinical Neuroscience 2002 9(3): 237-42.
Burne J A Essential and Parkinsonian tremor: a comparison of relative tremor amplitude in distal and proximal muscles of the same limb. Proceedings of Symposium on Tremor: Basic Mechanisms and Clinical Aspects, Kiel, Germany, 1997.
Burne J A, Blanche T. The effect of step changes in torque about the wrist on Parkinsonian and essential tremor. Proceedings of Symposium on Tremor: Basic Mechanisms and Clinical Aspects, Kiel, Germany, 1997.
3. Reflexes originating from tendon afferents
Electrical stimulation of muscle tendons results in strong inhibitory reflexes but the role of such reflexes is sill unclear yet the same reflexes are depressed in patients with severe muscle tremor.
Publications
Khan S, Burne JA.The effect of muscle length and electrode position on reflex inhibition following tendon electrical stimulation. Society for Neuroscience,Washington DC, 2005.
Khan S, Burne JA. The effect of reflex tendon inhibition on common cramp. Society for Neuroscience, Washington DC, 2005.
Rajagopalan A, Burne JA. A comparison of the reflex responses to electrical stimulation of cutaneous and tendon afferents. Society for Neuroscience, Washington DC, November 2005.
Haque, A.R.N.M.H., Burne, J.A., 2004. Ischemia sensitivity of the tonic stretch reflex of the ankle dorsiflexor over an extended frequency range of 25-60 Hz. Society of Neural Control of Movement, Spain, March, 2004.
Haque, A.R.N.M.H., Burne, J.A.,. The effect of background contraction and prolonged ischemia on the tendon reflex. 2003 Proceedings of Australian Physiological and Pharmacological Society, 33:40P.
Haque, A.R.N.M.H., Burne J.A., Turman, A.B., The ischemic response of the stretch reflex at different stretch frequencies. 2003. 33rd Conference of Society for Neuroscience, New Orleans, USA.
Burne J, Blanche T, Morris J. Electrical stimulation of muscle tendons in essential tremor. Muscle and Nerve 2002, 25:58-64
Burne JA & Lippold OC. Reflex inhibition following electrical stimulation over muscle tendons in man. Brain, 1996, 119, 1107-1114 .
Burne JA & Lippold OC. Loss of tendon organ inhibition in Parkinson's disease. Brain, 1996, 119, 1115-1121.
Burne JA, Blanche TJ. The response to muscle tendon stimulation in essential tremor. Clin Neurophysiol, 1999, 110, 2298.
Burne JA, Lippold OC Tendon organ inhibition in Parkinson's disease. Focus on Parkinson's Disease. 1998, 10:67-68.
4. Reflex disorders following injury to the nervous system
Studies of limb stiffness and reflex changes underlying muscle spasticity/rigidity/spasm in limbs affected by stroke, spinal cord injury and parkinsonism.
Publications
Burne JA, Carleton V, O'Dwyer N. The spasticity paradox: movement disorder or disorder of resting limbs. J. Neurol Neurosurg Psychiatry. 2005, 76:47-54.
Fung VS, Burne JA, Morris JG. Objective quantification of resting and activated parkinsonian rigidity I: A comparison of angular impulse and work scores. Movement Disorders. 2000, 15:48-55.
Burne JA, Carleton V, O'Dwyer N. Loss of task-dependent regulation of stretch reflex gain in stroke. 6th International Congress of Parkinson's disease and Movement Disorders, Barcelona, 2000.
Weekes N, Burne JA, Cathers I. Passive joint rotation as a therapy for spasticity following stroke. International Movement Disorders Society "Satellite meeting on muscle stiffness" 1999, P8, p24. Port Douglas, QLD, Aust.
Weekes N, Burne JA, Cathers I. A quantitative study of the tonic stretch reflex and hypertonia following stroke International Movement Disorders Society "Satellite meeting on muscle stiffness" 1999, P7, p23. Port Douglas, QLD, Aust.
Woolacott A, Burne J. Tonic stretch reflex activity and mechanical stiffness of the ankle joint following spinal cord injury. In: Pilowsky P (ed) Proceedings of the Australian Neuroscience Society. 2001.12:225.
5. Video image analysis and assessment of gait in movement disorders
Objective assessment of gait in movement disorders using automated analysis of whole body posture from standard video images.
Publications
Chang, R, Guan L & JA Burne (1997). A computer assisted image analysis system for diagnosing movement disorders Advanced Topics in Artificial Intelligence. A. Sattar. Springer - Verlag. Berlin. pp 290-301.
Chang R, Guan L & J.A. Burne Computer analysis of gait for diagnosing movement disorders. J. Disability and Rehabilitation. 2000, 22:97-108.
Green R, Guan L, Burne J (1998). A Real-time gait analysis for diagnosing movement disorders. Proceedings of the International Society for Optical Engineering Symposium on Medical Imaging, San Diego, USA.
T. Tan, L. Guan, Burne JA. (1999). A Real-Time Image Analysis System for Computer-Assisted Diagnosis of Neurological Disorders. J. Real-time Imaging. 5:253-269.
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Last update: 12th December 2007
