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Substances have to pass through the cell membrane in order to
enter or leave it. Oxygen and nutrients have to enter the cell
and carbon dioxide and other waste products need to leave the
cell.
If this transport does not occur, the cell would run out of oxygen
and nutrients and waste products would build up in the intracellular
fluid.
In the case of the amoeba, the exchange of substances occurs
directly with the intracellular fluid.
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